Works with any kind of brake!
The Cross Lever comes with the lever pivot pin in the hole closest to the handlebar for road calipers, center pull cantilever brakes, and road cable pull disk brakes.
Moving the pivot pin to the outer hole location makes the levers compatible with v-brakes and mountain cable disk brakes.
The Cross Lever can also be used on it's own. Just let the head of brake cable sit in the recess for the housing that runs between the two levers.
Note: For a lever that clamps on the "grip" area of a drop bar check out the Paul E-Lever.